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Dynamic Light Scattering (DLS), Dynamic Light Scattering (DLS), Mictrotrac Particle Characterization, Particle Size & Shape Analysis, Stability & Dispersibility Analysis

Microtrac NANOTRAC WAVE II Nanoparticle Size & Zeta Potential Analyzer – DLS | 0.3 nm–10 µm

All-in-one dynamic light scattering (DLS) analyzer — nanoparticle size, zeta potential, molecular weight and concentration from 0.3 nm to 10 µm in one compliant benchtop instrument.

  • ✔ Size 0.3 nm–10 µm · zeta ±200 mV · MW & concentration
  • ✔ 180° backscatter DLS · titration & temperature control
  • ✔ ISO 22412 · 21 CFR Part 11 data-integrity features
  • ✔ Lead time: configured to order — request current timeline
Prices follow supplier cost and stock availability and are updated regularly. The price you see is today's price — once you order, it's held for 7 days.
Install + training included Tailored service plan
0.3 nm–10 µm size range
±200 mV zeta range
ISO 22412 conformant
21 CFR 11 data integrity
Built for nanoparticle R&D teams

What your nano lab actually checks

Size, zeta and MW in one

Particle size, zeta potential (±200 mV), molecular weight and concentration on the same stable 180° backscatter optics — with automated titration for isoelectric point and temperature control. No second instrument, and calculations conform to ISO 22412 and 21 CFR Part 11.

An applications engineer on the line

Size, zeta, titration and compliance method development from engineers who run characterization in-house at ATO Lab. Sub-4h reply, NDA standard.

0.3 nm–10 µm
Size range
±200 mV
Zeta range
up to 40%
Concentration
20×10⁶ Da
Max mol. weight
ISO 22412
Standard
About this product

The Microtrac NANOTRAC WAVE II is an all-in-one dynamic light scattering (DLS) analyzer that measures nanoparticle size, zeta potential, molecular weight and concentration in a single compact benchtop instrument — 0.3 nm to 10 µm. It uses the same 180° backscatter Laser Amplified Detection and Frequency Power Spectrum model as the NANOTRAC series (up to 10⁶× the signal-to-noise of standard DLS), with temperature control, automated titration, and calculations conforming to ISO 22412 and 21 CFR Part 11.

Microtrac NANOTRAC WAVE II DLS nanoparticle size and zeta potential analyzer
The benchtop NANOTRAC WAVE II — size, zeta potential, molecular weight and concentration in one instrument.

Why nanoparticle labs choose the NANOTRAC WAVE II

Size, charge and molecular weight from one compliant instrument — no separate zeta analyzer.

Size + zeta + MW in one

Particle size (0.3 nm–10 µm), zeta potential (±200 mV), molecular weight and concentration on the same stable optics — no second instrument, no re-plumbing between measurements.

Robust zeta by field reversal

Rapid electric-field sequencing prevents electro-osmosis, and mobility is derived from the power-spectrum ratio — reliable charge even on high-concentration samples.

ISO 22412 & 21 CFR Part 11

DIMENSIONS LS calculates to ISO 22412 and supports 21 CFR Part 11 workflows — the data-integrity features regulated pharma and QC labs require.

Titration & temperature control

Automated titration maps zeta vs pH for isoelectric point, with active temperature control (+4 to +90 °C, ±0.1 °C) for stability and aggregation studies.

How Additive Plus supports it

A configured, installed analyzer with a size-and-zeta method dialed in on your material.

Step 01
Configure to your sample

We match the size and zeta cells, titration and solvent setup to your material and concentration before it ships.

Step 02
Install & train

Factory-trained engineers install and train your team on DIMENSIONS LS — size, zeta, MW and titration workflows.

Step 03
Method & QC support

We build the SOP — reproducible size and zeta reporting, isoelectric-point titrations and a 21 CFR Part 11 setup where needed.

What the NANOTRAC WAVE II measures

Full technical specifications are in the Specifications tab. Key measurement capability:

Parameter NANOTRAC WAVE II
Size range 0.3 nm – 10 µm (180° backscatter DLS)
Zeta potential −200 to +200 mV · size 10 nm – 20 µm · mobility 0–15 (µm/s)/(V/cm)
Also measures Molecular weight (<300 Da – 20×10⁶ Da), concentration, conductivity
Titration & temperature Automated titration · +4 to +90 °C, ±0.1 °C
Sample volume Size 50 µL – 3 mL · zeta 150 µL – 2 mL
Standards ISO 22412 · 21 CFR Part 11 features
Pharmaceutical nanoparticles and LNPs sized on the NANOTRAC WAVE II
Pharma & life sciences — LNP charge and protein stability.
Emulsions and colloids sized and charged on the NANOTRAC WAVE II
Colloids & emulsions — stability and isoelectric point.
Metal and ceramic nanomaterials characterized on the NANOTRAC WAVE II
Metal & ceramic nanomaterials — slip stability, zeta vs pH.

Typical applications

Where nanoparticle size and surface charge drive stability and performance.

Pharma & life sciences
LNP charge, protein stability
Colloids & emulsions
Stability & isoelectric point
Polymers & proteins
Size & molecular weight
Inks & pigments
Dispersion & charge control
Cosmetics & food
Emulsion & suspension QC
Ceramics & nanomaterials
Slip stability, zeta vs pH

Not sure the NANOTRAC WAVE II is the right analyzer?

A dip probe for reactions, dedicated charge titration, or larger particles.

Tell us whether you need size, zeta, molecular weight or all three, and your concentration and compliance needs — our applications engineer will confirm whether the WAVE II, the dip-probe FLEX or dedicated STABINO ZETA is the right fit, and can run your own sample first. Sub-4h reply, NDA standard.

Why source the NANOTRAC WAVE II through Additive Plus

  • Authorized US channel — sales, installation, training and service in one place.
  • We run powder and nanoparticle characterization in-house at ATO Lab — you talk to engineers who use these methods, not a ticket queue.
  • Method development on your material — size, zeta, MW, isoelectric-point titration and 21 CFR Part 11 SOPs.
  • Paid sample measurement before you commit — send us your dispersion and get the full size and zeta report. Sub-24h response, NDA standard.
Brand Microtrac
Country of origin Germany
Measurement principle Backscattered laser-amplified scattering reference method
Measuring range 0.3 nm - 10 µm
Calculation Model FFT power spectrum
Measurement angle 180°
Sample cell Various sample cell options
Zeta potential analysis yes
Zeta measurement range (potential) -200 mV - +200 mV
Zeta measurement range (size) 10 nm - 20 µm
Electrophoretic mobility 0 - 15 (µm/s) / (V/cm)
Conductivity measurement yes
Conductivity range 0 - 10 mS / cm
Molecular weight measurement yes
Molecular weight range <300 Da -> 20 x 10^6 Da
Temperature range +4°C - +90°C
Temperature accuracy ± 0.1°C
Temperature control yes
Temperature control range +4°C - +90°C
Titration yes
Reproducibility (size) =< 1%
Reproducibility (zeta) + / - 3%
Sample volume size measurement 50 µl - 3 ml
Sample volume zeta measurement 150 µl - 2 ml
Concentration measurement yes
Sample concentration up to 40 % (sample dependent)
Carrier fluids Water, polar and unpolar organic solvents, acid and base
Laser 780 nm, 3 mW; 2 laser diodes with zeta
Humidity 90 % non-condensing
Dimensions (W x H x D) 13.2×15×12.9 in / 355×381×330 mm

Product videos

Want to see it on your powder first?

We run this lab daily. Send a sample.

Send us a powder sample and we'll run PSD and morphology on the actual instrument, then share the data and method — so you see repeatability before you buy. We can also run analysis as a service while you evaluate.

Common questions

Don't see yours? Email [email protected] — NDA standard, typical reply within 4 hours.

What does the NANOTRAC WAVE II measure?
The NANOTRAC WAVE II measures nanoparticle size (0.3 nm–10 µm), zeta potential (−200 to +200 mV), molecular weight (below 300 Da up to 20×10⁶ Da), concentration and conductivity — all in one benchtop DLS instrument. It uses 180° backscatter Laser Amplified Detection with a Frequency Power Spectrum model, so size and charge come from the same stable optics without swapping instruments.
How does the WAVE II measure zeta potential?
Zeta is derived from electrophoretic mobility using the same power-spectrum method as sizing. Two coated probes on opposite sides of the zeta cell measure polarity (in a pulsed field) and mobility (in a high-frequency sine-wave field). Rapid field reversal prevents electro-osmosis, and mobility is calculated as a ratio of power spectra — which makes the measurement robust even at high concentration.
Can it measure concentrated samples without dilution?
Yes. Laser Amplified Detection and the 180° backscatter geometry let the NANOTRAC WAVE II measure both size and zeta at up to 40% concentration (sample-dependent), so you characterize the formulation as-is rather than a diluted proxy. That is important for concentrated pharmaceutical, colloid and ceramic-slip systems where dilution changes particle interactions.
Does it support zeta-vs-pH titration for isoelectric point?
Yes. The NANOTRAC WAVE II supports automated titration, so you can map zeta potential against pH and pinpoint the isoelectric point — the pH of minimum stability. Combined with temperature control (+4 to +90 °C, ±0.1 °C), it is well suited to stability, aggregation and shelf-life studies for suspensions and emulsions.
Is the NANOTRAC WAVE II suitable for regulated pharmaceutical QC?
Yes. DIMENSIONS LS calculates results in accordance with ISO 22412 for dynamic light scattering and supports 21 CFR Part 11 workflows — user administration, audit logging and electronic signatures. That makes the NANOTRAC WAVE II appropriate for regulated pharmaceutical and biopharma QC as well as R&D.
How is the WAVE II different from the NANOTRAC FLEX?
Both share the NANOTRAC DLS technology. The NANOTRAC WAVE II is a benchtop instrument that adds zeta potential, automated titration, temperature control and 21 CFR Part 11 support using measurement cells. The NANOTRAC FLEX uses a dip-in external probe (no cuvettes) for size only, ideal for in-situ reaction monitoring. Additive Plus helps you choose based on whether you need zeta and compliance, or probe-based flexibility.
What is the lead time, and can Additive Plus help set up a method?
The NANOTRAC WAVE II is configured to order; request a quote for the current lead time. Additive Plus is an authorized US channel and handles installation and DIMENSIONS LS training, then helps build your SOP — size, zeta, molecular weight, isoelectric-point titration and 21 CFR Part 11 where needed. You can also send a dispersion for a paid measurement first. Sub-4h reply, NDA standard.

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